At the end of each major draft, I leave time to quickly read through my entire MS, all at once, or as close to it as I can manage.
I skim quickly, reading as fast as I possibly can. My internal editor has been told that the draft is complete, and she's already out on the Lanai deck sipping Blue Hawaiians. I'm reading for voice, throwing in a few for-fun phrases along the way. I'm reading for plot inconsistencies, chapter after chapter blurring quickly together. I'm reading for typos and literary speed bumps that knock you out of the rhythm of the read.
But mostly I read to fall in love with my story again.
See, by the time I've wrenched through an entire draft, I'm ready to strangle my story, or possibly poison it to death with a slow-release toxin. I'm convinced that it's wretched garbage that should be thrown out, not foisted upon my lovely beta readers.
So I read it through quickly so I can fall in love with the story once more. I let myself be absorbed in that heady rush of emotion that entranced me in the first place.
What do you do at the end of a draft?